![]() Glomerulosclerosis is when the glomeruli become hard and scarred. These conditions can be autoimmune, genetic, or infection-related diseases. Glomerulonephritis refers to inflammation of the glomeruli. Causes range from environmental reasons to genetic ones. ![]() There are different types of glomerular diseases. Bowman’s capsule is especially vulnerable to diseases of the glomeruli (small blood vessels that Bowman’s capsule surrounds). What are the common conditions and disorders that affect Bowman’s capsule?ĭiseases and conditions that affect your kidneys also affect Bowman’s capsule. As the fluids are leaving, water and nutrients are reabsorbed. The blood pressure in the glomerulus (the glomerular blood hydrostatic pressure) helps to move the blood along. This system is the way that blood is cleaned and returned to your body, while waste materials are sent out of your body as urine through tubules (tiny tubes). When you’re healthy, protein and cell content can’t get through. The way they are joined creates slits that let some things go through but stops other things. These pedicles link together like they’re holding hands (“interdigitation”). These podocytes have pedicles that look like fingers. The inner layer of the capsule is the visceral layer, and it’s made up of cells called podocytes. This layer is made of body tissue known as simple squamous epithelium. One is the outer layer, called the parietal layer. You need a microscope to see Bowman’s capsule. ![]() Each kidney is connected to your bladder by a tube called a ureter. The kidneys reside between your intestines and diaphragm. Usually, there is one kidney on either side of your spine. The kidneys are located below your ribcage and behind your belly. Children produce less urine than adults, and the amount produced depends on their age.Bowman’s capsule is located in the renal cortex, part of your kidney. Most of the water and other substances that filter through your glomeruli are returned to your blood by the tubules. In a single day, your kidneys filter about 150 quarts of blood. Your blood circulates through your kidneys many times a day. In the nephron, your blood is filtered by the tiny blood vessels of the glomeruli and then flows out of your kidney through the renal vein. This large blood vessel branches into smaller and smaller blood vessels until the blood reaches the nephrons. How does blood flow through my kidneys?īlood flows into your kidney through the renal artery. The remaining fluid and wastes in the tubule become urine. The tubule helps remove excess acid from the blood. As the filtered fluid moves along the tubule, the blood vessel reabsorbs almost all of the water, along with minerals and nutrients your body needs. ![]() The tubule returns needed substances to your blood and removes wastesĪ blood vessel runs alongside the tubule. Larger molecules, such as proteins and blood cells, stay in the blood vessel. The thin walls of the glomerulus allow smaller molecules, wastes, and fluid-mostly water-to pass into the tubule. The glomerulus filters your bloodĪs blood flows into each nephron, it enters a cluster of tiny blood vessels-the glomerulus. Each nephron has a glomerulus to filter your blood and a tubule that returns needed substances to your blood and pulls out additional wastes. ![]()
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